Fri Aug 19 2022

22 articles - From Friday Aug 12 2022 to Friday Aug 19 2022

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Guidelines

Guidelines, position statements, white papers, technical reviews, consensus statements, etc…

Pancreatology

coMpliAnce with evideNce-based cliniCal guidelines in the managemenT of acute biliaRy pancreAtitis): The MANCTRA-1 international audit.

The results of this study showed an overall poor compliance with evidence-based guidelines in the management of ABP, with wide variability based on the admitting speciality. Study protocol registered in ClinicalTrials.Gov (ID Number NCT04747990).

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Meta-analysis

meta-analyses and systematic reviews

Liver Transpl

Clinical Outcomes of Patients with LI-RADS 3 or LI-RADS 4 Observations in Patients with Cirrhosis: A Systematic Review.

LR-3 and 4 observations have elevated but variable risk of HCC. Higher quality studies are necessary to identify high-risk patients who warrant close CT or MRI-based follow-up.

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Pancreas

The Impact of Pancreatic Enzyme Replacement Therapy on Patients With Advanced Pancreatic Adenocarcinoma: A Systematic Review and Narrative Synthesis.

Patient and health professional education is required because there seems to be a general lack of awareness about the use of PERT in pancreatic cancer. Systematic Review Registration: PROSPERO 2020 CRD42020195986.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Intake of mother's milk by very low birth weight infants and variation in DNA methylation of genes involved in neurodevelopment at 5.5 years.

In-hospital % MM intake by VLBW infants was associated with variations in DNAm of neurodevelopmental genes at 5.5 years; some of these DNAm variations are associated with brain structure and IQ. Clinical Trial Registration ISRCTN35317141 at isrctn.com and NCT02759809 at clinicaltrials.gov.

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Liver Transpl

Combined liver transplant and sleeve gastrectomy: report of a brief-interval staged approach.

This proof-of-concept study revealed that a brief-interval SG during LT is feasible in patients with high MELD and resulted in sustained weight loss at 1-year with similar graft survival. Further studies are needed to determine an optimal strategy.

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Outcomes of Acute Liver Failure patients listed for Liver Transplantation: A Multicenter Prospective Cohort Analysis.

Post-LT outcomes for ALF are excellent in this cohort of very ill patients. The development of multi-organ failure whilst on the transplant list and APAP ALF etiology were associated with a lower likelihood of successful receipt of LT.

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Pancreas

Neurofibromatosis Type 1: A Rare Predisposition for Gastrinomas and Other Neuroendocrine Tumors.

Zollinger-Ellison syndrome is an important condition, which should be kept in mind in the patient with NF-1 who presents with recurrent peptic ulceration and diarrhea. The emerging association between these 2 conditions is being examined on a cellular and immunohistochemical level.

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Treatment of Microcirculatory Disturbances in Acute Pancreatitis: Where Are We Now?

The prophylactic use of antibiotics is not recommended. The treatment outcome of acute pancreatitis is still unsatisfactory.

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Pancreatology

Pancreatic exocrine insufficiency following pancreatoduodenectomy: A prospective bi-center study.

This prospective study found a high incidence of PEI after PD with persisting symptoms in one-to two thirds of al patients. Limited attention was paid to vitamin deficiencies. Improved screening and treatment strategies for PEI and vitamins need to be designed.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Liver Transpl

Liver allocation policies for hepatocellular carcinoma have leveled the playing field - but who should be playing?

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Low-Dose Aspirin, Rejection, and Thrombosis: Is it the Wonder Drug® of Liver Transplantation?

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Novel Approaches Are Needed to Study Social Determinants of Health in Liver Transplantation.

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Letters&Replies

Letters to the editors and authors’ replies

Liver Transpl

Access to liver transplantation for patients with severe acute-on-chronic liver failure in Europe.

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Causes of variability in listing and access to liver transplantation for critically ill cirrhotic patients: acknowledging the elephant in the room.

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Others

all remaining publications eg case reports, images of the month, etc…

Am J Clin Nutr

Bias Against the Keto Diet.

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Pancreas

Agenesis of Dorsal Pancreas With Chronic Calcific Pancreatitis: The Head Without a Body.

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Bifurcated Main Pancreatic Duct With Pancreatic Stone Impaction Leading to Acute Cholangitis: A Case Report.

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Diffuse Pancreatic Serous Cystic Neoplasm: A Rare Cause of Pancreatic Insufficiency.

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Identification of Anaerobic Organism Infection in a Patient With Emphysematous Pancreatitis Based on Metagenomic Next-Generation Sequencing: A Case Report.

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Plasma Osteopontin Levels as an Early Predictor of Mortality in Acute Pancreatitis: A Preliminary Study.

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Unusual Case of Delayed Rupture of Pancreatic Neuroendocrine Tumor After Endoscopic Ultrasound and Biopsy.

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Validation of Serum MicroRNAs-19a, -24, and -29a as Potential Markers to Differentiate Pancreatic Cancer-Associated Diabetes From Type 2 Diabetes Mellitus.

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